A novel brominated cuparene-derived sesquiterpene ether from the red alga Laurencia sp.

Abstract

A novel brominated cuparene-derived sesquiterpene ether, 8,10-dibromo-3,7-epoxy-laur-13-ol (1), was isolated from Laurencia sp. collected in South China Sea. Besides this, two known sesquiterpenes, (9β)-aristol-1(10)-en-9-ol (2) and aristolone (3), were also yielded, and aristolone (3) was obtained from Laurencia for the first time. Their structures were elucidated by spectroscopic methods.

Keywords:

• Laurencia
• sesquiterpene
• cuparene-derived sesquiterpene ether
• 8,10-dibromo-3,7-epoxy-laur-13-ol

Acknowledgements

This work was financially supported by the Union Opening Foundation of CAS Key Laboratory of Marine Bio-resources Sustainable Utilization (LMB) and Guangdong Key Laboratory of Marine Materia Medica (LMM) and the National Natural Science Foundation of China (Grant No. 20872006).