Two new flavonoid glycosides from the whole herbs of Hyssopus officinalis

Abstract

Two new flavonoid glycosides, quercetin 7-O-β-d-apiofuranosyl-(1 → 2)-β-d-xylopyranoside (1) and quercetin 7-O-β-d-apiofuranosyl-(1 → 2)-β-d-xylopyranoside 3′-O-β-d-glucopyranoside (2), together with nine known flavonoids were isolated from the whole herbs of Hyssopus officinalis L. cultivated in Xinjiang Uygur Autonomous Region of China. All structures were characterized by the spectroscopic methods including UV, IR, ESI-MS, 1D, and 2D NMR. Their potent free radical scavenging activity against the stable 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical was evaluated.

Keywords:

• Hyssopus officinalis L.
• flavonoid
• quercetin 7-O-β-d-apiofuranosyl-(1 → 2)-β-d-xylopyranoside
• quercetin 7-O-β-d-apiofuranosyl-(1 → 2)-β-d-xylopyranoside 3′-O-β-d-glucopyranoside
• free radical scavenging activity
• DPPH