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Original Articles

A new phenanthrenequinone from Dendrobium draconis

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Pages 251-255 | Received 17 Sep 2010, Accepted 06 Dec 2010, Published online: 15 Mar 2011
 

Abstract

A number of Dendrobium species (Orchidaceae) have been used as health foods. In Thailand, the tea prepared from the stems of Dendrobium draconis Rchb.f. (Orchidaceae) has been used as a blood tonic. Our phytochemical investigation of this plant led to the isolation of a new compound namely 5-methoxy-7-hydroxy-9,10-dihydro-1,4-phenanthrenequinone (1), along with four known stilbenoids including hircinol (2), gigantol (3), batatasin III (4), and 7-methoxy-9,10-dihydrophenanthrene-2,4,5-triol (5). The structures of these compounds were determined through extensive spectroscopic studies, including 1H and 13C NMR, DEPT, COSY, NOESY, HMQC, HMBC, ESI-MS, and HR-ESI-MS experiments. In the DPPH-free radical assay, these stilbene derivatives showed appreciable antioxidant activity.

Acknowledgements

This work was supported by the National Research University Project of CHE and the Ratchadaphiseksomphot Endowment Fund (FW1016A). M.A. is grateful to the Chulalongkorn University Graduate School for a research scholarship, and the Research Instrument Center of the Faculty of Pharmaceutical Sciences for research facilities. We thank Prof. T. Phadungcharoen for the plant identification.

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