Secondary metabolites from the roots of Phlomis umbrosa

Abstract

The phytochemical study of the roots of Phlomis umbrosa Turcz afforded a new phenylethanoid glycoside, 3-hydroxy-4-methoxy-β-phenylethoxy-O-[2,3-diacetyl-α-l-rhamnopyranosyl-(1 → 3)]-4-O-cis-feruloyl-[β-d-apiofuranosyl-(1 → 6)]-β-d-glucopyranoside (1), and two new 28-noroleanane-derived spirocyclic triterpenoids, phlomishexaol C (2) and phlomishexaol D (3). Their structures were elucidated on the basis of 1D and 2D NMR analyses, in combination with high-resolution MS experiment.

Keywords:

• Phlomis umbrosa
• rhizomes
• phenylethanoid glycoside
• nortriterpenoids

Acknowledgements

This work was supported by the funds from Henan University of Science and Technology (no. 09001334, 2007QN018) and High-Tech R&D Program Grant from Henan Government of China (no. 092102210182).