A new aristolactam-type alkaloid from the roots of Aristolochia fangchi

Abstract

Phytochemical investigation of 85% ethanol extracts from the roots of Aristolochia fangchi yielded a new aristolactam derivative named 6-methoxyl aristolactam I N-β-glucoside (1), together with four known compounds, aristolactam IVa (2), aristolactam I-β-d-glucoside (3), aristolactam I (4), and aristolactam-N-β-d-glucoside (5). Their structures were elucidated by spectral analysis. The cytotoxicity of the isolated compounds was also determined.

Keywords:

• Aristolochiaceae
• Aristolochia fangchi
• 6-methoxyl aristolactam I N-β-glucoside
• cytotoxicity