Three new cycloartane glycosides from Nervilia fordii

Abstract

From the water-soluble extract of the aerial part of herbal plant Nervilia fordii, three new cycloartane glycosides, named as nervisides A (1), B (2), and C (3), were isolated. Their structures were elucidated through a combination of spectroscopic analysis and hydrolysis. At the same time, the new compounds were tested for their cytotoxicities in vitro against human tumor cell lines (CNE, Hep-2, and HepG2) using MTT method.

Keywords:

• Nervilia fordii
• nerviside
• cycloartane glycoside
• cytotoxicity

Acknowledgments

This research is financially supported by the Foundation (No. 8351063201000003) of Guangdong Natural Sciences Committee. The authors are grateful to Ms Chun-Chi Feng and Ms Xiao-Lin Feng for the measure of all NMR spectra, and to Ms Hui-Nan Zhao and Ms Bei Jiang for the measure of HR-ESI-MS.