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A new triterpenoid saponin from Sanguisorba officinalis

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Pages 607-611 | Received 15 Nov 2011, Accepted 08 Mar 2012, Published online: 15 May 2012
 

Abstract

A new 19-oxo-18,19-seco-ursane-type triterpenoid saponin, named sanguisoside A (1), along with nine known triterpenoid saponins (210), was isolated from the roots of Sanguisorba officinalis. Their structures were determined on the basis of spectroscopic analysis and chemical method. Compounds 2 and 3 showed cytotoxic activity against SGC-7901, SMMC-7721, A549, and DU145 cell lines.

Acknowledgements

This project was financially supported by Promotive Research Fund for Young and Middle-aged Scientists of Shandong Province (No. BS2009SW062) and Key Laboratory for Rare and Uncommon Diseases of Shandong Province.

Notes

1. These authors contributed equally to this work.

Additional information

Notes on contributors

Pei-Yuan Zhang

1

San-Hai Qin

1

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