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Journal of Asian Natural Products Research Volume 14, 2012 - Issue 7
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A new sesquiterpene lactone from Elephantopus tomentosus

Bei Wang Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, 571101, China; Tropical Crops Genetic Resources Institute, Chinese Academy of Tropical Agriculture Sciences, Danzhou, 571737, China; Horticultural and Garden College, Hainan University, Haikou, 570228, ChinaView further author information
,
Wen-Li Mei Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, 571101, ChinaView further author information
,
Yan-Bo Zeng Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, 571101, China
,
Zhi-Kai Guo Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, 571101, China
,
Guo-Dao Liu Tropical Crops Genetic Resources Institute, Chinese Academy of Tropical Agriculture Sciences, Danzhou, 571737, ChinaCorrespondence[email protected]
&
Hao-Fu Dai Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, 571101, ChinaCorrespondence[email protected]
Pages 700-703 | Received 30 Dec 2011, Accepted 30 Mar 2012, Published online: 15 May 2012
 
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Abstract

A new sesquiterpene lactone, named tomenphantopin H (1), together with two known germacranolides, 2β-methoxy-2-deethoxy-8-O-deacylphantomolin-8-O-tiglinate (2) and 2-deethoxy-2-hydroxyphantomolin (3), was isolated from the whole plant of Elephantopus tomentosus Linn. The new compound was completely elucidated using a combination of 1D and 2D NMR techniques (COSY, HMQC, and HMBC) and HR-ESI-MS analyses. All compounds exhibited antibacterial activity.

Acknowledgements

This study was financially supported by National Nonprofit Institute Research Grant of CATAS-TCGRI (No. PZS083).

Notes

1. These authors contributed equally to this work.

Additional information

Notes on contributors

Bei Wang

1

Wen-Li Mei

1

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