Butanolide derivatives from the bark of Machilus yaoshansis

Abstract

Six new butanolide derivatives with long aliphatic side chains (1–6), together with 23 known lipophilic constituents, were isolated from the bark of Machilus yaoshansis. Their structures were elucidated by spectroscopic and chemical methods. All the isolates were evaluated for cytotoxic and anti-inflammatory activities.

Keywords:

• Lauraceae
• Machilus yaoshansis
• butanolide derivatives
• cytotoxic and anti-inflammtory activities

Acknowledgments

Financial support from the National Natural Sciences Foundation of China (NNSFC; Grant Nos 81102341, 30825044, and 20932007), and the National Science and Technology Project of China (Nos 2009ZX09311-004 and 2009ZX09301-003-4-1) is acknowledged.