Two new diterpenoids from Croton crassifolius

Abstract

Two new clerodane-type diterpenoids were isolated from the roots of Croton crassifolius Geisel. The structures of these compounds were elucidated as 9-[2-(2(5H)-furanone-4-yl)ethyl]-4,8,9-trimethyl-1,2,3,4,5,6,7,8-octahydronaphthalene-4-carboxylic acid (1) and methyl 9-[2-(2(5H)-furanone-4-yl)ethyl]-4,8,9-trimethyl-1,2,3,4,5,6,7,8-octahydronaphthalene-4-carboxylic ester (2) by spectroscopic methods.

Keywords:

• Euphorbiaceae
• Croton crassifolius
• clerodane-type diterpenoid

Acknowledgments

This study was financially supported by the National Natural Science Foundation of China (Nos 20772047 and 21310104) and Natural Science Foundation of Guangdong Province (No. 32210018).