Four new triterpenes from the endemic relict shrub Tetraena mongolica

Sheng-An Tang Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy, Research Center of basic Medical Sciences, Tianjin Medical University, Tianjin, 300070, China

Lin-Lin Ding Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy, Research Center of basic Medical Sciences, Tianjin Medical University, Tianjin, 300070, China

Hui-Yuan Zhai Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy, Research Center of basic Medical Sciences, Tianjin Medical University, Tianjin, 300070, China

Nan Qin Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy, Research Center of basic Medical Sciences, Tianjin Medical University, Tianjin, 300070, China

Hong-Quan Duan Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy, Research Center of basic Medical Sciences, Tianjin Medical University, Tianjin, 300070, ChinaCorrespondence[email protected]

Abstract

A chemical investigation of the endemic relict shrub Tetraena mongolica led to the isolation of four new triterpenes: 11α,12α:13β,28-diepoxyoleanane-3β-yl trans-caffeate (1), 3β-hydroxy-11α,12α-epoxyoleanane-28-al (2), olean-11-en-28-al-3β-yl trans-caffeate (3), and 28-acetoxy-olean-12-en-3β-yl trans-caffeate (4). Their structures were elucidated by extensive spectroscopic methods.

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Acknowledgments

This work was partially supported by the Natural Science Foundation of Tianjin, China (Grant Nos 11JCZDJC20900 and 10JCYBJC15000).

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Four new triterpenes from the endemic relict shrub Tetraena mongolica

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Four new triterpenes from the endemic relict shrub Tetraena mongolica

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