Two new taraxasterol-type triterpenes from Pergularia tomentosa growing wild in Algeria

Abstract

Two new triterpenes of the taraxasterol skeleton are isolated for the first time form Pergularia tomentosa L. of Algerian origin. The new compounds were named pergularine A (7) and pergularine B (8). In addition, eight known compounds were isolated from the plant including oleic acid, (9Z,12Z)-octadecadienoic acid, α-amyrin, 3-acetyltaraxasterol, 3-taraxasterol, 16α-hydroxytaraxasterol-3-acetate, 3-epi-micromeric acid, and (9Z,12Z)-octadecadienoic acid glucoside. All known compounds are isolated for the first time from P. tomentosa L.

Keywords:

• Pergularia tomentosa
• Asclepiadaceae
• pergularine A
• pergularine B
• taraxasterol triterpenes

Acknowledgements

The authors wish to thank Miss Fatima Mustafa and Miss Areeg Jaber at the Chemistry Department, University of Jordan for recording the NMR and Mass spectra, respectively.