Two new acetylated flavonoid glycosides from Phyllanthus urinaria

Abstract

Two new acetylated flavonoid glycosides, quercetin 3-O-α-l-(2,4-di-O-acetyl) rhamnopyranoside-7-O-α-l-rhamnopyranoside (1) and quercetin 3-O-α-l-(3,4-di-O-acetyl) rhamnopyranoside-7-O-α-l-rhamnopyranoside (2), together with two known compounds, quercetin (3) and quercetin 3-O-α-l-rhamnopyranoside (4), were isolated from the ethanol extract of Phyllanthus urinaria. The structures of the new compounds were determined on the basis of extensive spectroscopic data including IR, HR-ESI-MS, 1D NMR, and 2D NMR.

Keywords:

• Euphorbiaceae
• Phyllanthus urinaria
• acetylated flavonoid glycoside

Acknowledgments

This research was financially supported by the National Natural Science Foundation of China (No. 30873245), the Science and Technology Project of Shenzhen city of China (No. 201202154), and the Chinese National S&T Special Project on Major New Drug Innovation (2011ZX09307-002-01). The authors are grateful to Dr Ying-Hui Duan, Mr Lai-Ming Li, and Mr Xiao-Jie Zen, Institute of Traditional Chinese Medicine and Natural Products, Jinan University, for measuring the HR-ESI-MS and NMR spectral data.