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Abstract
Three new isopimarane diterpenoids named excoecarins F–H (1–3) were isolated from the EtOAc extract of the Chinese ethnodrug Gua-jing-ban (Excoecaria acerifolia Didr.). Their structures were elucidated by the analysis of spectroscopic data including 1D, 2D NMR and HR-MS. The anti-HIV-1 bioactivity test of 1 and 2 showed weak activity.
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Acknowledgments
This work was financially supported by Special Fund for Agro-scientific Research in the Public Interest (201303117), National Support Science and Technology Subject (2013BAI11B04), and the Fundamental Scientific Research Funds for CATAS (1630052013001; ITBB110301). The authors thank the members of the analytical group of the State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, for the spectral measurements.