Four new sesquiterpenoids from cultures of the fungus Funalia trogii

Jian-Hai Ding School of Chemical Science and Technology, Yunnan University, Kunming, 650091, China; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China

Tao Feng State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China

Zheng-Hui Li State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China

Jing Si nstitute of Microbiology, Beijing Forestry University, Beijing, 100083, China

Hai-You Yu nstitute of Microbiology, Beijing Forestry University, Beijing, 100083, China

Hong-Bin Zhang School of Chemical Science and Technology, Yunnan University, Kunming, 650091, China

Ji-Kai Liu State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, ChinaCorrespondence[email protected]

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Abstract

Four new drimane sesquiterpenoids, named as funatrols A–D (1–4), together with isodrimenediol (5), were isolated from cultures of the fungus Funalia trogii. The new structures were elucidated by means of spectroscopic methods. All compounds were tested for their cytotoxicities against five human cancer cell lines.

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Acknowledgments

This work was financially supported by National Basic Research Program of China (973 Program, 2009CB522300), the National Natural Science Foundation of China (U1132607).

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Four new sesquiterpenoids from cultures of the fungus Funalia trogii

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Four new sesquiterpenoids from cultures of the fungus Funalia trogii

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