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Abstract
Two new benzyl derivatives, aspergentisyl A (1) and aspergentisyl B (2), as well as one new naphthoquinone derivative, aspergiodiquinone (3), together with seven known prenylated benzaldehyde derivatives (4–10) were isolated from the marine-derived fungus Aspergillus glaucus HB1-19. The structures of these compounds were characterized based on 1D and 2D NMR spectra analyses and comparison with those reported in the literature. In addition, each isolate was tested for its 1,1-diphenyl-2-picrylhydrazyl radical-scavenging property and all these compounds except compound 3 exhibited strong radical-scavenging activity.
Acknowledgments
This work was financially supported by the Chinese National Science Fund (Nos. 30973627 and 41176120), the National High Technology Research and Development Program of China (No. 2013AA092901), the Public Projects of State Oceanic Administration (No. 2010418022-3), the Shandong Promotive Research Fund for Excellent Young and Middle-aged Scientists (No. BS2010HZ027), and the Program for Changjiang Scholars and Innovative Research Team in University (No. IRT0944). We thank Dr Raymond Andersen of University of British Colombia, Canada, and Dr Robert Keyzers of Victoria University of Wellington, New Zealand, for helping with manuscript preparation.