Two new schisdilactone-type compounds from Schisandra chinensis

Abstract

Two new schisdilactone-type compounds, respectively, named schisdilactone H (1) and schisdilactone I (2), were isolated from the stems of Schisandra chinensis. The structures and absolute configurations of these new compounds were elucidated by extensive spectroscopic analysis as well as time-dependent density functional theory electronic circular dichroism calculations.

Keywords::

• Schisandra chinensis
• schisdilactone
• structure elucidation
• epimer

Acknowledgments

This work was supported by the National Natural Science Foundation of China (Grant No. 81102797), Talent Project Fund (Grant No. 201102) and General Research Fund (Grant No. YB201012) from Gannan Medical University to L.-H. Wu.