Two new phenylpropanoid glycosides from the roots of Aruncus sylvester

Abstract

Two new phenylpropanoid glycosides, 1,3,4-tri-O-(E)-caffeoyl-β-d-glucopyranoside (1) and 1,4-di-O-(E)-caffeoyl-β-d-glucopyranoside (2), along with four known phenylpropanoid glycosides (3–6), were isolated from the roots of Aruncus sylvester. The structures of 1 and 2 were elucidated using various spectroscopic methods. Compounds 1 and 2 displayed significant scavenging activity of 2,2-diphenyl-1-picrylhydrazyl free radicals with IC₅₀ values of 110 and 258 μM (ascorbic acid: IC₅₀ = 574 μM).

Keywords::

• Rosaceae
• phenylpropanoid glycosides
• Aruncus sylvester
• Aruncus
• anti-oxidant

Acknowledgements

Financial support from Program for New Century Excellent Talents in University (NCET-09-0589), China Postdoctoral Science Foundation (No. 20090450657), and Tianjin Municipal Science and Technology Commission (No. 11ZCGHHZ00800) is gratefully acknowledged.