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Abstract
Two new triterpenesaponins, ilexsaponins G and H (1 and 2), together with six known triterpenesaponins (3–8), were isolated from the roots of Ilex pubescens. Their structures were elucidated on the basis of spectroscopic evidence and hydrolysis products. Those compounds showed inhibitory activities against two human colorectal cancer cell lines HCT 116 and HT-29.
Acknowledgments
This work was financially supported by the National Natural Science Fund of China (Grant No. 81202897); the Chunhui Project of Ministry of Education (Z2010102); the Chun hui Project of Ministry of Education (Z2010103); the Open Research Fund of Key Laboratory of Food Biotechnology, Xihua University (SZJJ2014-008); and the Innovation Fund of Postgraduate, Xihua University (YCJJ2014106).