Antimicrobial constituents from the flowers of Trollius chinensis

Dan-Yi LiKey Laboratory of Structure-Based Drug Design & Discovery, Shenyang Pharmaceutical University, Ministry of Education, Shenyang110016, China;School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang110016, China

Jin-Xia WeiKey Laboratory of Structure-Based Drug Design & Discovery, Shenyang Pharmaceutical University, Ministry of Education, Shenyang110016, China;School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang110016, China

Hui-Ming HuaKey Laboratory of Structure-Based Drug Design & Discovery, Shenyang Pharmaceutical University, Ministry of Education, Shenyang110016, China;School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang110016, ChinaCorrespondence[email protected] [email protected]

Zhan-Lin LiKey Laboratory of Structure-Based Drug Design & Discovery, Shenyang Pharmaceutical University, Ministry of Education, Shenyang110016, China;School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang110016, ChinaCorrespondence[email protected] [email protected]

Abstract

A new 1-aryl-isochroman, trolliusol A (1), was isolated from the flowers of Trollius chinensis, along with seven known phenolic compounds in an antimicrobial activity-directed phytochemical investigation. The structures of these compounds were elucidated by spectroscopic methods, and their inhibitory activities against one fungus and four bacterial strains were measured.

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Acknowledgments

This work was financially supported by the Program for Innovative Research Team of the Ministry of Education and Program for Liaoning Innovative Research Team in University.

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Antimicrobial constituents from the flowers of Trollius chinensis

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Antimicrobial constituents from the flowers of Trollius chinensis

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