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Hepatic metabolism: a key component of herbal drugs research

, , , , &
Pages 89-106 | Received 12 May 2014, Accepted 28 Aug 2014, Published online: 08 Oct 2014
 

Abstract

Liver is the largest metabolic organ for a wide range of endogenous and exogenous compounds and plays a crucial part in the pharmacokinetics and pharmacodynamics through various metabolic reactions. This review provides a progressive description of hepatic metabolism of herbal drugs with respect to metabolic types and investigational methods. In addition, the problems encountered during the research process are discussed.

Acknowledgements

This work was financially supported by NSFC (No. 81073018 and No. 81274044).

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