Eight new bibenzyl derivatives from Dendrobium candidum

Abstract

Eight bibenzyl derivatives, namely dendrocandins J–Q (1–8), were isolated from the stems of Dendrobium candidum. Their structures were elucidated by 1D and 2D NMR experiments and mass spectrometry. Compounds 1–8 were examined for antioxidant activity by 1,1-diphenyl-2-picrylhydrazyl free radical scavenging assay, and the IC₅₀ values were 36.8, 70.2, 45.0, 60.5, 87.6, 50.4, 22.3, and 30.3 μM, respectively.

Keywords::

• Dendrobium candidum
• bibenzyl derivatives
• dendrocandins J–Q
• antioxidant activity

Acknowledgments

This research work was financially supported by the National Natural Sciences Foundation of China (No. 31170016), PIRTI-IT1302, and Doctor Station Fund for Priority Development Field (20131106130002).