Lignans from the bark of Zanthoxylum simulans

Abstract

Investigation on the EtOAc extract of the bark of Zanthoxylum simulans led to the isolation of four new lignans including zanthoxylumin A (1), zanthoxylumin B (2), ( − )-magnolin (3), and ( − )-pinoresinol-di-3,3-dimethylallyl ether (4). Their structures were established by comprehensive analysis of the spectral data, especially 1D and 2D NMR spectra.

Keywords::

• Zanthoxylum simulans
• Rutaceae
• lignans

Acknowledgements

This work was financially supported by the National Natural Science Foundation of China (No. 31170336), a Project from the Traditional Chinese Medicine Scientific Research Fund of Hunan Province, China (No. 201122), and a Project from Science and Technology Innovative Research Team in Higher Educational Institutions of Hunan Province, China (No. 15).

Notes

^1. These authors contributed equally to this paper.