Two new cucurbitane-type triterpenoid saponins isolated from ethyl acetate extract of Citrullus colocynthis fruit

Abstract

Two new cucurbitacins I (1 and 2), together with eight known compounds (3–10), were isolated from the ethyl acetate extract of the fruit of Citrullus colocynthis. Compounds 3, 5–9 were isolated from C. colocynthis for the first time. The structures of new compounds were determined primarily from IR, HR-MS, 1D-, and 2D-NMR analysis.

Keywords::

• Cucurbitaceae
• Citrullus colocynthis
• cucurbitane-type triterpenoids
• cucurbitacin

Acknowledgments

This work was financially supported by the Start-Up Foundation for Young Scientists of Shihezi University (RCZX201120) and Outstanding Youth Project of Shihezi University (2013ZRKXYQ-YD01, KF201402).

Disclosure statement

No potential conflict of interest was reported by the authors.