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Abstract
A new 2-arylbenzofuran compound, 5-dehydroxy-moracin U (1), along with 10 known compounds (2–11), were isolated from cell cultures of Morus alba. Their structures were elucidated on the basis of extensive spectroscopic analyses. The anti-inflammatory activity assay of 1–8 showed that 2 and 8 exhibited significant inhibitory effect on LPS-induced NO production with the values of 76.4% and 98.7% at 10− 5 M, respectively.
Disclosure statement
No potential conflict of interest was reported by the authors.
Notes
1. These authors contributed equally to this work.
Additional information
Funding
This work was financially supported by the National Natural Science Foundation of China [Grant No. 81273405], the Fundamental Research Funds for the Central Universities [Grant No. 2012N06], the Program for Doctorate Education [Grant No. 20111106110029], and the National Science & Technology Major Project “Key New Drug Creation and Manufacturing,” China [No. 2012X09301002-001-005].