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Pericoterpenoid A, a new bioactive cadinane-type sesquiterpene from Periconia sp.

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Pages 671-675 | Received 06 Mar 2015, Accepted 05 May 2015, Published online: 22 Jun 2015
 

Abstract

Pericoterpenoid A (1), a new cadinane-type sesquiterpene, was isolated from an endolichenic fungal strain Periconia sp. (No. 19-4-2-1). Its structure was characterized by analyzing the spectroscopic data (IR, MS, 1D- and 2D-NMR). The antimicrobial activity against Escherichia coli, Staphylococcus aureus, Aspergillus niger, and Candida albicans was evaluated. Pericoterpenoid A showed moderate antimicrobial activity against A. niger and weak activity against C. albicans. This is the first report of the presence of cadinane-type sesquiterpene in Periconia sp.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Notes

Dedicated to Prof. Xin-Sheng Yao on the occasion of his 80th birthday.

1. These authors contributed equally to this work.

Additional information

Funding

This work was financially supported by the Ministry of Science and Technology of China [grant number 2012ZX09301002-003001006], the National Natural Science Foundation of China [grant number 81422054], [grant number 81373306], the Guangdong Natural Science Funds for Distinguished Young Scholar [grant number S2013050014287], Guangdong Province Universities and Colleges Pearl River Scholar Funded Scheme, and the State Key Laboratory of Pharmaceutical Biotechnology [grant number KF-GN-201412].

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