New norterpenoids and a sphingolipid from Carissa opaca

Abstract

Chemical investigations on the aerial parts of Carissa opaca resulted in the isolation and characterization of two new nor-triterpenoids (compounds 1 and 2) and a new sphingolipid (compound 3) together with six known compounds. The structures of all the isolates were established using spectral data. All the isolated compounds showed DPPH radical scavenging and enzyme inhibitory activities against enzymes acetylcholinesterase, butyrylcholinesterase, and lipoxygenase.

Keywords::

• Carissa opaca
• nor-triterpenoid
• sphingolipid
• acetylcholinesterase inhibition
• butyrylcholinesterase inhibition
• lipoxygenase inhibition

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

We are thankful to Higher Education Commission (HEC) of Pakistan for providing financial aid to the indigenous Ph.D. scholars of our laboratory.