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Abstract
Two new iridoid glucosides, callicoside A (1) and callicoside B (2), were isolated from the leaves of Callicarpa nudiflora. Their structures were elucidated by means of spectroscopic methods and chemical evidences. In an in vitro bioassay, compound 1 showed pronounced hepatoprotective activity against D-galactosamine-induced toxicity in WB-F344 rat hepatic epithelial stem-like cells.
Acknowledgment
We thank Prof. Ai-Hong Liu at Center of Analysis and Testing Nanchang University for NMR measurements.
Disclosure statement
No potential conflict of interest was reported by the authors.
Additional information
Funding
Financial support was provided by the National Natural Science Foundation of China (NSFC, [grant number 81373955]), Natural Science Foundation of Jiangxi, China [grant number 20142BAB205085], and Fund for the Development of Youth in Inspection Institute of Research (No. 2013WA9).