A new phenylethanoid glycoside from Incarvillea compacta

Abstract

A new phenylethanoid glycoside, 3′′′-O-methylcampneoside I (1), was isolated from the 90% ethanolic extract of the roots of Incarvillea compacta, together with three known compounds, campneoside I (2), ilicifolioside A (3), and campneoside II (4). Their structures were determined spectroscopically and compared with previously reported spectral data. Compound 1 existed as epimers and displayed better 1,1-diphenyl-2-picrylhydrazyl (DPPH)-free radical scavenging activity using di-tert-butyl-4-methylphenol (BHT) as the positive control. In addition, pretreatment of human HepG2 cells with compound 1 significantly increased the viability on CCl₄-induced cell death.

Keywords:

• Bignoniaceae
• Incarvillea compacta
• hepatoprotective effect
• antioxidant activity
• phenylethanoid glycoside
• 3′′′-O-methylcampneoside I

Disclosure statement

No potential conflict of interest was reported by the authors.