Diterpenoid alkaloids from the roots of Aconitum brachypodum Diels

Abstract

A new diterpenoid alkaloid, named bullatine H (1), along with 10 known diterpenoid alkaloids were isolated from the roots of Aconitum brachypodum Diels (Ranunculaceae). The structure of 1 was elucidated by analysis of its spectroscopic data. It should be noted that compound 1 is the first example with 11, 13-dioxygenated denudatine-type diterpenoid alkaloid isolated from Aconitum brachypodum.

Keywords:

• Ranunculaceae
• Aconitum brachypodum
• diterpenoid alkaloids
• isolation
• structure elucidation

Acknowledgments

The authors are grateful to State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences for the measurements of NMR and MS spectroscopic data.