Three new isobenzofuranone derivatives from the fruiting bodies of Hericium erinaceus

Abstract

Three new isobenzofuranone derivatives erinaceolactones D-F (1–3), together with four known ones (4–7), were isolated from the fruiting bodies of Hericium erinaceus. Their structures were determined on the basis of comprehensive spectroscopic analyses including UV, 1D, 2D NMR and HR-TOF-MS. The absolute configuration of erinaceolactone D (1) and erinaceolactone E (2) were assigned by comparing their specific rotation with those of analogs in literatures. The four known compounds were isomers with each other and were isolated simultaneously for the first time.

Keywords:

• Hericium erinaceus
• isobenzofuranone
• erinaceolactone D
• erinaceolactone E
• erinaceolactone F