Lobophylins F-H: three new cembrene diterpenoids from soft coral Lobophytum crassum

Tarik A. MohamedPhytochemistry Department, National Research Centre, Giza, Egypt

Abdelsamed I. ElshamyNatural Compounds Chemistry Department, National Research Centre, Giza, EgyptCorrespondence[email protected]

Taha A. HussienFaculty of Pharmacy, Pharmacognosy Department, University of Sciences and Technology, Ibb, Yemen

Jui-Hsin SuGraduate Institute of Marine Biotechnology, National Dong Hwa University, Pingtung, Taiwan;Industry Academia Collaboration Center, National Museum of Marine Biology and Aquarium, Pingtung, Taiwan

Jyh-Horng SheuDepartment of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung, Taiwan;Frontier Center for Ocean Science and Technology, National Sun Yat-sen University, Kaohsiung, Taiwan;Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung, Taiwan

Mohamed Elamir F. HegazyPhytochemistry Department, National Research Centre, Giza, Egypt

Abstract

Three new cembrenoids, lobophylins F-H (1–3), along with three known ones, lobophylins A-C (4–6), were isolated from the ethyl acetate extract of the Taiwan water soft coral Lobophytum crassum. The structures of isolated cembrenoids were elucidated on the basis of extensive spectroscopic methods such as IR, 1D, 2D NMR and HR–ESI–MS.

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Lobophylins F-H: three new cembrene diterpenoids from soft coral Lobophytum crassum

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Lobophylins F-H: three new cembrene diterpenoids from soft coral Lobophytum crassum

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