Two new prenylated isoflavones from Hedysarum multijugum

Abstract

Chemical investigation on the ethyl acetate extract of the roots of Hedysarum multijugum resulted in the isolation of two new prenylated isoflavonoids: 5, 7, 2′-trihydroxy-4′-methoxy-3′-(γ, γ-dimethylallyl) isoflavone (hedysarimisoflavone A, 1) and 5, 7, 2′-trihydroxy-4′-methoxy-6, 8-di-(γ, γ-dimethylallyl) isoflavone (hedysarimisoflavone B, 2). Their structures were elucidated on the basis of spectroscopic analyses, especially, ¹H and ¹³C NMR spectra in conjunction with their 2D experiments, ¹H-¹H COSY, HMQC, HMBC, and NOESY.

Keywords:

• Leguminosae
• Hedysarum multijugum
• isoflavones
• hedysarimisoflavone A
• hedysarimisoflavone B