Two new compounds from the green peel of Juglans mandshurica

Jing LiXiangya School of Pharmaceutical Sciences, Central South University, Changsha410013, China

Kang-Ping XuXiangya School of Pharmaceutical Sciences, Central South University, Changsha410013, China

Zhen-Xing ZouXiangya School of Pharmaceutical Sciences, Central South University, Changsha410013, China

Hui ZouXiangya School of Pharmaceutical Sciences, Central South University, Changsha410013, China

Hong-Ping LongThe First Hospital of Hunan University of Chinese Medicine, Changsha410007, China

Lei-Hong TanXiangya School of Pharmaceutical Sciences, Central South University, Changsha410013, ChinaCorrespondence[email protected]

Rui-Huan LiuXiangya School of Pharmaceutical Sciences, Central South University, Changsha410013, China

Yi-Kun WangXiangya School of Pharmaceutical Sciences, Central South University, Changsha410013, China

Ping-Sheng XuXiangya Hospital of Central South University, Changsha410008, China

Gui-Shan TanXiangya School of Pharmaceutical Sciences, Central South University, Changsha410013, China;Xiangya Hospital of Central South University, Changsha410008, ChinaCorrespondence[email protected]

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Abstract

A new cyclic diarylheptanoid (1) and a new flavone glucoside (2), along with seven known compounds, were isolated from the green peel of Juglans mandshurica. Their structures were elucidated based on extensive spectroscopic analyses. Moreover, the cytotoxicity against NCI-H460, A549, and K562 cancer cells of compounds 1–6 was evaluated. The results showed that compound 3 exhibited moderate inhibitory potency against the growth of three cell lines.

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Acknowledgments

The authors gratefully acknowledge the NMR measurements from the Modern Analysis and Testing Centre of CSU.

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Two new compounds from the green peel of Juglans mandshurica

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Two new compounds from the green peel of Juglans mandshurica

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