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Abstract
Two previously undescribed sesquiterpenes along with nine known compounds were isolated from the fermentation broth of Aspergillus fumigatus, an endophyte of Ligusticum wallichii. Their structures were elucidated through extensive spectroscopic analysis combined with quantum chemical ECD calculations. Two new compounds exhibited moderate growth inhibition against MV4-11 and MDA-MB-231 cell lines.
Graphical Abstract
Disclosure statement
No potential conflict of interest was reported by the authors.
Acknowledgments
The authors wish to thank Dr. Jing Yang (Kunming Institute of Botany, Chinese Academy of Sciences) for the help in ECD calculation.
Additional information
Funding
This research was funded by Sichuan Provincial Youth Science and Technology Innovation Team (2016TD0006, 2015TD0028); China Postdoctoral Science Foundation (2017M622985).
