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Abstract
Two new nordammarane-type triterpenoids, 3β-acetoxy-20-oxo-21-nordammaran-23-carboxylic acid methyl ester (1) and 3β-acetoxy-17β-dammaranic acid (2), along with two known cycloartane-type triterpenoids (3–4), were isolated from the petroleum ether-soluble extract of Artemisia argyi. Their structures were elucidated based on 1D and 2D NMR spectroscopic data analysis. All compounds were evaluated for their α-glucosidase inhibitory activity in vitro. Compounds 1–4 exhibited significant inhibitory effects on α-glucosidase with IC50 values ranging from 38.34 ± 0.23 to 105.54 ± 0.33 μM.
Graphical Abstract
Disclosure statement
No potential conflict of interest was reported by the authors.
Funding
This research was financially supported by grants from the National Natural Science Foundation of China [grant number 31400305 and 81773898] and the Project for Youth Backbone Teachers in the University of Henan Province [grant number 2015GGJS-130].
Correction Statement
This article has been republished with minor changes. These changes do not impact the academic content of the article.