A new brominated polyacetylene from Chinese marine sponge Xestospongia testudinaria

Min Yang State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences , Shanghai 201203, China; ; University of Chinese Academy of Sciences , Beijing 100049, China; View further author information

Lin-Fu Liang State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences , Shanghai 201203, China; ; College of Materials Science and Engineering, Central South University of Forestry and Technology , Changsha 410004, China; View further author information

Li-Gong Yao State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences , Shanghai 201203, China; View further author information

Hai-Li Liu State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences , Shanghai 201203, China; View further author information

Yue-Wei Guo State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences , Shanghai 201203, China; ; University of Chinese Academy of Sciences , Beijing 100049, China; ; Open Studio for Druggability Research of Marine Natural Products, Pilot National Laboratory for Marine Science and Technology , Qingdao 266237, ChinaCorrespondence[email protected] [email protected]
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Abstract

A new brominated polyacetylene xestonariene J (1), bearing a rare 2,4-dibromo-1-ene-3-yne terminal in the molecule, along with two known related analogues (2 and 3), was obtained from Chinese marine sponge Xestospongia testudinaria. Its structure was determined on the basis of detailed spectroscopic analysis and comparison with literature data.

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No potential conflict of interest was reported by the authors.

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Funding

This research work was financially supported by the National Natural Science Foundation of China (Nos. 81520108028 and 41476063), the NSFC-Shandong Joint Fund for Marine Science Research Centers (No. U1606403), and the SKLDR/SIMM Project (No. SIMM1705ZZ-01).

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A new brominated polyacetylene from Chinese marine sponge Xestospongia testudinaria

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A new brominated polyacetylene from Chinese marine sponge Xestospongia testudinaria

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