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Abstract
The phytochemical study of the ethanol extract of the leaves and twigs of Rhododendron decorum afforded a new ascorbic acid derivative (1), a new ionone analogue (2), a new ursane-type triterpenoid glucoside (3), and four known compounds (4−7). The structures were elucidated by spectroscopic analyses, including HRESIMS, 1D, and 2D NMR. The anti-neuroinflammatory activities of the compounds were evaluated by measuring inhibitory effects of LPS-induced NO production in BV2 cells.
GRAPHICAL ABSTRACT
Acknowledgment
The authors are grateful to the Department of Instrumental Analysis of our institute for the UV, IR, NMR and MS spectra measurements.
Disclosure statement
No potential conflict of interest was reported by the authors.
Additional information
Funding
This work was financially supported by grants from the National Natural Science Foundation of China (Nos. 21572274, 21732008, and 81630094) and the CAMS Innovation Fund for Medical Sciences (No. 2016-I2M-3-012).