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Original Articles

Three new diterpenoids from Aralia dumetorum

, , , , , , & show all
Pages 308-315 | Received 29 Sep 2018, Accepted 06 Jan 2019, Published online: 04 Mar 2019
 

Abstract

Three new diterpenoids, dumetoranes A (1) and B (2), melanocane B (3), together with four known ones including melanocane A (4), ent-15S,16-dihydroxypimar-8(14)-en-19-oic acid (5), ent-pimara-8(14),15-diene-19-oic acid (6), and ent-pimara-8(14),15-diene-19-ol (7) were obtained from the ethanol extract of the roots of Aralia dumetorum. Their structure elucidation was achieved by the methods of spectroscopic HRMS, IR, NMR, and by comparison with literature. The cytotoxicities of compounds 13 and 5 were assayed by in vitro MTT methods.

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work was financially supported by the NSFC [grant number 81460535] and the Yunnan Provincial Applied Basic Research Projects [grant number 2017FD122].

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