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Articles

Structural characterization and biological evaluation of chemical constituents from Ilex cornuta

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Pages 316-328 | Received 19 Nov 2018, Accepted 11 Jan 2019, Published online: 01 Mar 2019
 

Abstract

One new ursane-type triterpenoid (1), one new ursane-type triterpenoid glycoside (2), and one new oleanane-type triterpenoid glycoside (3), along with 20 known compounds, were isolated from the leaves of Ilex cornuta. The structures of these natural products were elucidated on the basis of detailed spectroscopic analyses and chemical derivation. Our biological evaluation established that selective compounds showed moderate to significant antioxidant activities in the 1,1-diphenyl-2-picrylhydrazyl and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) methods.

Graphical Abstract

Acknowledgments

We also thank Professor Jie Zhou for the identification of the plant materials.

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work was funded by National Natural Science Foundation of China (No. 21807040), Natural Science Foundation of Shandong Province (Nos. ZR201709210256 and JQ201721), the Young Taishan Scholars Program (No. tsqn20161037), Foundation from University of Jinan (No. 160100203), Shandong Talents Team Cultivation Plan of University Preponderant Discipline (No. 10027), and Error! Hyperlink reference not valid. (No. 2015RC015).

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