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Articles

New dibenzodioxocinone and pyran-3,5-dione derivatives from the deep-sea-derived fungus Penicillium canescens SCSIO z053

, , , , &
Pages 338-345 | Received 06 Dec 2018, Accepted 18 Jan 2019, Published online: 05 Mar 2019
 

Abstract

A new isopentylated dibenzodioxocinone, canescenin A (1), and a new isopentylated pyran-3,5-dione derivative, canescenin B (2), were isolated from an extract of the deep-sea-derived fungus Penicillium canescens SCSIO z053. Their structures were elucidated by spectroscopic analysis. It was rare to obtain pyran-3,5-dione derivatives from nature. Antibacterial, cytotoxic, and antiviral activities of 1 and 2 were also evaluated.

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Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

The authors are grateful for the financial support provided by the Natural Science Foundation of China (81673326), Strategic Leading Special Science and Technology Program of Chinese Academy of Sciences (XDA100304002), and Regional Innovation Demonstration Project of Guangdong Province Marine Economic Development (GD2012-D01-002).

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