A new lignan glycoside from Astragalus yunnanensis

Abstract

A new lignan glycoside, astrayunoside A (1), along with eight known compounds (2–9), were obtained from the methanol extract of roots of Astragalus yunnanensis. All the compounds were obtained from A. yunnanensis for the first time. Their structures were elucidated by extensive spectroscopic analysis (1D and 2D-NMR, MS, UV, CD, and IR). The weak antibacterial activities of the crude extracts of A. yunnanensis against Staphyloccocus aureus, Escherichia coli, Proteus vulgaris, Pseudomonas aeruginosa, Shigella dysenteriae, Salmonella typhi H901, Candida albicans, Streptococcus mutans, and Actinomyces viscosus were observed.

Graphical Abstract

Keywords:

• Leguminosae
• Astragalus yunnanensis
• lignan glycoside
• antibacterial activity

Acknowledgments

The authors are grateful to Librarian Ling-Yun Jiang of The Library of Dali University for his kindly help with information retrieval.

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

The work was financially supported by the National Natural Science Foundation of China [31170313, 81460532].