Two new alcohol glycosides from the roots of Paeonia intermedia C. A. Meyer

Abstract

Two new alcohol glycosides, 1-O-β-d-glucopyranosyl-deoxypaeonisuffrone (1) and 9-O-β-d-apiofuranoyl-(1→6)-β-d-glucopyranosyl-xanthoarnol (2), together with eight known compounds (3–10), have been isolated from the dried roots of Paeonia intermedia C. A. Meyer. Their structures were mainly elucidated on the basis of ESIMS, one- and two-dimensional NMR techniques. Antibacterial activities of compounds 1–10 were evaluated, and compounds 9 and 10 showed antibacterial activities against Staphylococcus argenteus CMCC26003 and Escherichia coli CMCC44103.

Keywords:

• Ranunculaceae
• Paeonia intermedia
• alcohol glycoside
• antibacterial activity

Acknowledgement

We thank Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy, Jinan University for the HRESIMS measurement.

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work was financially supported by the National Natural Science Foundation of China (Grant No. 81603275) and the China Postdoctoral Science Foundation (Grant No. 2016M602697, No. 2018T110988).