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Chemical constituent with cytotoxicity from Sterculia diversifolia

, , , &
Pages 899-905 | Received 09 Jan 2020, Accepted 27 Jun 2020, Published online: 11 Jul 2020
 

Abstract

One new coumarin (stercularin), along with eleven known compounds, was isolated for the first time from ethyl acetate fraction of Sterculia diversifolia. The structures of isolated compounds were characterized by spectroscopic techniques such as EIMS, 1H-NMR and 13C-NMR. Compound 1 showed significant cytotoxicity by brine shrimp lethality assay (LD50: 8.00 μg/ml) and PC-3 cell lines protocol (IC50: 3.92 ± 0.20 μg/ml), respectively.

Graphical abstract

Disclosure statement

We declare that we have no conflict of interest.

Additional information

Funding

This study was self-funded.

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