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Abstract
A new homo-aro-cholestane glycoside parispolyside H, along with nine known compounds, were isolated from 75% ethanolic extract of the rhizome of Paris polyphylla var. chinensis. Their chemical structures were elucidated on the basic of analysis of detailed spectroscopic and physicochemical properties. In addition, the isolated compounds (1, 6-9) were evaluated for their cytotoxic activity against HepG2 human liver cancer cell lines. Among them, four known compounds (6-9) showed cytotoxicity with IC50 values ranging from 0.41 to 3.6 μM.
Disclosure statement
No potential conflict of interest was reported by the authors.
Additional information
Funding
This work was financially supported by National Key R&D Program of China (Grant No. 2017YFC1701900), National Standardization Project of Traditional Chinese Medicine (Grant No. ZYBZH-Y-FJ-09), and the Special Scientific Research Projects in Traditional Chinese Medicine Industry (Grant No. 201507002).
