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Articles

Two new 2-phenylethylchromones from artificial agarwood by holing method

, , , , , & show all
Pages 1156-1163 | Received 15 Apr 2020, Accepted 02 Dec 2020, Published online: 18 Dec 2020
 

Abstract

Two new 2-(2-phenylethyl)chromone derivatives (12) were isolated from the ethyl acetate extract of artificial agarwood induced by holing method originating from Aquilaria sinensis (Lour.) Gilg, and they were isolated from this genus for the first time. The structures of these two new compounds were elucidated by extensive spectroscopic analyses, including UV, IR, one- and two-dimensional NMR and HRESIMS measurements. Bioassay tests of these two new compounds showed compounds 1 and 2 had weak inhibitory activity against acetylcholinesterase at a concentration of 50.0 μg/ml.

Graphical abstract

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This study was financially supported by the Key Research and Development Project of Hainan Province (ZDYF2017101, ZDYF2019217 and ZDYF2019203), China Agriculture Research System (CARS-21), the key Research and Development Project of China (2018YFC1706404).

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