168
Views
1
CrossRef citations to date
0
Altmetric
Articles

Two new sesquiterpene aryl esters from Armillaria gallica 012m

, , , , , , , , , & show all
Pages 59-65 | Received 08 Sep 2020, Accepted 14 Jan 2021, Published online: 29 Jan 2021
 

Abstract

Two new sesquiterpene aryl esters, armimelleolides A and B (1 and 2), and four known ones, were isolated from the EtOAc extract of Armillaria gallica 012 m by column chromatography on silica gel, reversed-phase C18 silica gel and semi-preparative HPLC. Their structures were elucidated on the basis of spectroscopic methods, including extensive 1 D NMR, 2 D NMR and MS. All these compounds showed potential antitumor activities against at least one of the human cancer cell lines (A549, HCT-116, M231 and W256), with IC50 ranging from 2.57 to 19.94 μM.

Graphical abstract

Disclosure statement

No potential conflict of interest was reported by the authors.

Funding

This project was in part supported financially by the National Natural Science Foundation of China (Nos.31760096, 31960095, 81660717, and 81960777), Yunnan Ten-thousand Talents Program to W.-G.W., the National Natural Science Foundation of Yunnan Provinces (No. 2019FB027). Yunnan Provincial Science and Technology Department–– Applied Basic Research Joint Special Funds of Yunnan University of Traditional Chinese Medicine [grant number 2019FF002(-005), 2018FF001(-029)].

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.