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Research Article

Neolignan and phenylpropanoid compounds from the resin of Styrax tonkinensis

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Pages 527-535 | Received 15 Dec 2019, Accepted 23 Mar 2021, Published online: 12 Apr 2021
 

Abstract

A new neolignan compound, tonkinensisin A (1), and two phenylpropanoid compounds, tonkinensisin B (2) and tonkinensisin C (3), were isolated from the resin of Styrax tonkinensis (Pierre) Craib ex Hartw. The structures of these compounds were determined by spectroscopic analysis, and the relative configurations of compounds 1 and 3 were determined by J-based configuration analysis (JBCA) method. All compounds were assayed for cytotoxic activities against five tumor cell lines (HepG-2, A549, Hela, MCF-7, and PC-3) by CCK-8 test in vitro.

Graphical Abstract

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

We greatly acknowledge the financial supports from the Provincial Key Platforms and Major Scientific Research Projects of Guangdong Universities (No. 2017KTSCX101), the National Natural Science Foundation of China (No. 81773884), and Scientific Research Projects of Health Commission of Hubei Province (No. WJ2019M258).

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