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Abstract
Phytochemical investigation on the 95% alcohol extract of the aerial part of Inula japonica led to the isolation of three new compounds, inulanolides F-G (1-2) and 17α-carboxaldehyde-ent-kaur-18-oic acid (3), together with four known compounds (4–7). The structures of new compounds were elucidated by using spectroscopic data. Most of the isolated compounds showed significant anti-inflammatory activities.
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Disclosure statement
No potential conflict of interest was reported by the authors.
Additional information
Funding
We gratefully acknowledge grants from the Drug Innovation Major Project of China (No. 2018ZX09735001-002-005), the National Natural Science Foundation of China (No. 81773863), the Science and Technology Commission of Shanghai Municipality (No. 18401932600), the Youth Innovation Promotion Association (No. 2019284), the National Science and Technology Major Project (No. 2019ZX09201004-003-041 and 2019ZX09201004-003-042), and technological innovation action plan of Shanghai Science and Technology Commission (No. 19401971800).
