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Abstract
Three new sesquiterpene polyol ester compounds angulatins S-U, together with three known compounds were isolated from Celastrus angulatus Maxim. According to mainly 1D NMR and 2D NMR analysis, the structures of the new compounds were completely determined as angulatin S (1β-furoyloxy-2β,8α-diisobutanoyloxy-9β-benzoyloxy-15-acetoxy-4α,6α-dihydroxy-β-dihydroagarofuran), angulatin T (1β,2β,6α-triacetoxy-8β,15-diisobutanoyloxy-9α-benzoyloxy-β-dihydroagrofuran), and angulatin U (1β,6α,15-triacetoxy-8β-isobutanoyloxy-9α-benzoyloxy-β-dihydroagarofuran).
Graphical abstract
Acknowledgments
We are grateful to Mr. W. G. Zhu, J. X. Kang, J. H. Zhao, and C. S. Zhuang for the NMR, ESI, and IR measurements.
Disclosure statement
No potential conflict of interest was reported by the author(s).
Additional information
Funding
This work was financially supported by grants from The Drug Innovation Major Project (2018ZX09711001-008-004).